Weight Gain from Birth to Adolescence and TyG Index at Age 18 Years: A Cohort Study in Northeast Brazil.

BACKGROUND: Developmental models suggest that the phenotypes may arise from an immediate or mediated adaptive metabolic response of the perinatal growth. Evidence on the cumulative effects of growth and factors associated with risk of insulin resistance in adolescents is lacking. OBJECTIVE: To investigate the association between birthweight, weight gain during infancy, childhood and adolescence and the triglyceride-glucose index in adolescents. METHODS: This is a cohort of 217 children born at term, followed for the first six months, and reassessed at 8 and 18 years of age. The variables of interest were birthweight, postnatal growth defined as rapid postnatal growth when the weight gain from birth to six months of age was greater than 0.67 z-score, and the same criterion was used for high BMI gain from ages 6 months to 8 years, and from 8 to 18 years. Socioeconomic condition, nutritional status, practice of physical exercises and consumption of ultra-processed foods were verified. Multivariate linear regression analysis was used to verify the effect of the variables on the triglyceride-glucose index. RESULTS: Birthweight was not associated with triglyceride-glucose index in adolescence. Rapid postnatal growth during the first 6 months, higher BMI gain from 8 to 18 years and higher waist circumference contributed significantly to explain higher triglyceride-glucose index. CONCLUSION FOR PRACTICE: Our findings suggest that rapid postnatal growth may be one of the first signs of a higher triglyceride-glucose index in adolescence and that attention should be paid to the greater gain in body mass between childhood and adolescence for the risk of a higher triglyceride-glucose index.

Determining factors of child linear growth from the viewpoint of Bronfenbrenner's Bioecological Theory

Abstract Objective To analyze the factors associated with children's linear growth, according to the different subsystems of the 6Cs model and Bronfenbrenner's Bioecological Theory. Data sources Narrative review, carried out in the Scielo, Lilacs, Pubmed, and Science Direct databases, based on research using the terms Bioecological Theory, child growth, and risk factors, combined with the use of Boolean operators. Summary of findings According to the 6Cs model, proposed based on Bronfenbrenner's Bioecological Theory, the determining factors of children's linear growth are in six interrelated subsystems - cell, child, clan, community, country/state and culture. The empirical studies included in this review made it possible to analyze protection and risk factors within the subsystems. Among the protective factors: are adequate birth weight and satisfactory weight gain, breastfeeding for six months or more; proper hygienic habit of hand washing, proper elimination of feces, and access to clean water. As risk factors: low, birth weight and size, prematurity, multiple deliveries, short interval between deliveries, non-exclusive breastfeeding until the 3rd month, frequency and severity of infectious processes and anemia, little parental education, short maternal statur, inadequate maternal nutritional status, domestic violence, family poverty, food, and nutritional insecurity, living in rural areas or at high altitudes. Conclusion Children's linear growth is determined by interrelated factors that encompass aspects prior to the child's birth, as well as socioeconomic, political, family and community issues.

Birthweight, postnatal growth and blood pressure in adolescents of low socioeconomic condition: a cohort study in Northeast Brazil.

OBJECTIVE: To verify the influence of low birth weight and rapid postnatal weight gain and associated factors on blood pressure in adolescence in a population of low socioeconomic status, considering that injuries occur in the perinatal period can be predictors of future metabolic changes and are still poorly explored. METHODS: A cohort study was carried out with 208 adolescents, 78 born with low weight and 130 born with appropriate weight. The infants were followed up during the first six postnatal months and reassessed at 8 and 18 years of age. The independent variables were birthweight and postnatal weight gain. Rapid postnatal weight gain was defined when above 0.67 z score. The co-variables were sex, maternal height and family income at birth, nutritional status at eight years old, socioeconomic conditions, nutritional status, fat mass index, and physical activity level at 18 years. The outcome variable was blood pressure at 18 years old. The bivariate and multivariable logistic regression analysis were realized and p < 0,05 was considered significant. RESULTS: The proportion of adolescents with elevated blood pressure was 37.5%. The multivariable logistic regression analysis showed the variables independently associated with a higher chance of elevated blood pressure in adolescence were rapid postnatal weight gain (OR = 2.74; 95% CI 1.22-6.14; p = 0.014), male sex (OR = 4.15; 95% CI 1.66-10.38; p = 0.002) and being physically active (OR = 2.70; 95% CI 1.08-6.74; p = 0.034). CONCLUSIONS: The rapid postnatal weight gain was a predictor for elevated blood pressure in adolescence, independently of other factors.

Determining factors of child linear growth from the viewpoint of Bronfenbrenner's Bioecological Theory.

OBJECTIVE: To analyze the factors associated with children's linear growth, according to the different subsystems of the 6Cs model and Bronfenbrenner's Bioecological Theory. DATA SOURCES: Narrative review, carried out in the Scielo, Lilacs, Pubmed, and Science Direct databases, based on research using the terms Bioecological Theory, child growth, and risk factors, combined with the use of Boolean operators. SUMMARY OF FINDINGS: According to the 6Cs model, proposed based on Bronfenbrenner's Bioecological Theory, the determining factors of children's linear growth are in six interrelated subsystems - cell, child, clan, community, country/state and culture. The empirical studies included in this review made it possible to analyze protection and risk factors within the subsystems. Among the protective factors: are adequate birth weight and satisfactory weight gain, breastfeeding for six months or more; proper hygienic habit of hand washing, proper elimination of feces, and access to clean water. As risk factors: low, birth weight and size, prematurity, multiple deliveries, short interval between deliveries, non-exclusive breastfeeding until the 3rd month, frequency and severity of infectious processes and anemia, little parental education, short maternal statur, inadequate maternal nutritional status, domestic violence, family poverty, food, and nutritional insecurity, living in rural areas or at high altitudes. CONCLUSION: Children's linear growth is determined by interrelated factors that encompass aspects prior to the child's birth, as well as socioeconomic, political, family and community issues.

Birthweight, postnatal growth and blood pressure in adolescents of low socioeconomic condition: a cohort study in Northeast Brazil

Abstract Objective To verify the influence of low birth weight and rapid postnatal weight gain and associated factors on blood pressure in adolescence in a population of low socioeconomic status, considering that injuries occur in the perinatal period can be predictors of future metabolic changes and are still poorly explored. Methods A cohort study was carried out with 208 adolescents, 78 born with low weight and 130 born with appropriate weight. The infants were followed up during the first six postnatal months and reassessed at 8 and 18 years of age. The independent variables were birthweight and postnatal weight gain. Rapid postnatal weight gain was defined when above 0.67 z score. The co-variables were sex, maternal height and family income at birth, nutritional status at eight years old, socioeconomic conditions, nutritional status, fat mass index, and physical activity level at 18 years. The outcome variable was blood pressure at 18 years old. The bivariate and multivariable logistic regression analysis were realized and p < 0,05 was considered significant. Results The proportion of adolescents with elevated blood pressure was 37.5%. The multivariable logistic regression analysis showed the variables independently associated with a higher chance of elevated blood pressure in adolescence were rapid postnatal weight gain (OR = 2.74; 95% CI 1.22-6.14; p= 0.014), male sex (OR = 4.15; 95% CI 1.66-10.38; p= 0.002) and being physically active (OR = 2.70; 95% CI 1.08-6.74; p= 0.034). Conclusions The rapid postnatal weight gain was a predictor for elevated blood pressure in adolescence, independently of other factors.

Salutogenesis, nutritional status and eating behaviour: a systematic review.

OBJECTIVE: To assess the relationship between the sense of coherence (SOC), eating behaviour and nutritional status. DESIGN: It is a systematic review. SETTING: The following databases were searched: MEDLINE/PubMed, Science Direct/Elsevier, LILACS/Bireme, SciELO and Google Scholar, using the indexed terms 'salutogenesis', 'sense of coherence', 'nutritional status', 'nutrition', 'eating behavior' and 'healthy eating'. The indexed terms were used in Portuguese and English according to the database searched. The data were extracted in a standardised way and the quality of the studies was assessed using the Newcastle-Ottawa Scale. PARTICIPANTS: Observational studies were included, with no limitations on the date of publication or language. RESULTS: After reading the titles and abstracts of 1855 articles, 107 full texts were retrieved, of which 27 were included. Of these, twenty-five were cross-sectional and two were longitudinal. The average score for Newcastle-Ottawa studies was 6 and most studies were rated as moderate and low quality. The cumulative sample size of all included studies was 28 981 adults and the elderly, aged between 18 and 81 years. The studies were carried out in fifteen different countries. Fifteen articles assessed eating behaviour/habit and twelve assessed nutritional status. Studies have shown that SOC has a positive relationship with an appropriate eating behaviour/habit. On the other hand, the relationship between SOC and nutritional status was controversial among studies. The heterogeneity of the data resulting from the use of different methods of evaluation of the outcomes of interest (nutritional status and eating behaviour) made it impossible to perform a meta-analysis. CONCLUSION: SOC was positively associated with adequate eating behaviour. However, it was not possible to establish a relationship between SOC and nutritional status.

Situação de insegurança alimentar em domicílios de Pernambuco, Região Nordeste do Brasil: contribuições para discussão da violação do direito à alimentação / Food insecurity in households in Pernambuco, Northeast region of Brazil: contributions to the discussion on the violation of the right to adequate food

Resumo O objetivo deste estudo foi investigar os fatores associados à insegurança alimentar em domicílios do Estado de Pernambuco, localizado na região Nordeste do Brasil. Trata-se de um estudo transversal realizado em 1.008 domicílios particulares. Para a investigação, utilizou-se a Escala Brasileira de Insegurança Alimentar (EBIA) e foram analisadas associações com variáveis socioeconômicas, demográficas e práticas relacionadas à alimentação. Calculou-se razão de prevalência e ajuste por meio da regressão de Poisson, sendo estatisticamente significantes aquelas associações cujo p≤0,05. Encontrou-se prevalência de 68,4% de insegurança alimentar. Apresentaram associação com insegurança: escolaridade do chefe da família; renda per capita; participação no programa Bolsa Família; número de moradores; regime de ocupação do domicílio; classe social; práticas; e opiniões acerca da alimentação da família. O maior risco de insegurança foi encontrado naqueles com pior condição econômica, em beneficiários do Bolsa Família e naqueles que indicavam a falta de produtos ultraprocessados para melhorar a alimentação da família. Observou-se insegurança alimentar atrelada às condições de vulnerabilidade social e àqueles que não consideravam ter uma boa alimentação. Grande parte dos sujeitos referiram utilizar os recursos do Bolsa Família para aquisição de alimentos, o que reforça a importância dessa estratégia na promoção do acesso à alimentação.

Abstract This study aimed to investigate factors associated with food insecurity in households in the state of Pernambuco, in the Northeast region of Brazil. This is a cross-sectional study carried out in 1,008 private households. The investigation used the Brazilian Food Insecurity Scale (EBIA) and analyzed associations with socioeconomic and demographic variables, as well as practices related to eating. Prevalence ratio and adjustment were calculated using Poisson regression, and associations where p ≤ 0.05 were statistically significant. Food insecurity prevalence was 68.4%. Variables associated with insecurity were: education of the head of the family; per capita income; participation in the Bolsa Família Program; number of residents; occupation of the household; social class; practices and opinions about family eating habits. The greatest insecurity risk was found in those with the worst economic conditions, in beneficiaries of the Bolsa Família Program and in those who considered the lack of ultra-processed products to improve the family's diet. Food insecurity was linked to conditions of social vulnerability and to those who did not perceive that they had a good diet. Most of the subjects reported using resources of the Bolsa Família program to purchase food, which reinforces the importance of this strategy in promoting access to food.

Oral Health Care of Children and Adolescents with Different Impairments of Cerebral Palsy: Barriers and Challenges

Abstract Objective: To evaluate the barriers to access and oral health care faced by children and adolescents with Cerebral Palsy (CP) according to their motor impairment through the perception of caregivers. Material and Methods: A case series study was carried out at three health institutions in Pernambuco, Brazil. The study sample consisted of 94 caregivers of 5-to-18-year-old patients with CP, according to GMFCS (The Gross Motor Function Classification System). Data were collected using a semi-structured form to evaluate the barriers to access and analyzed statistically by the chi-square and Fisher exact tests, adopting a 5% level of significance. In addition, binary logistic regression was performed to determine the weight of the variables in explaining the outcome variable. Results: There were major difficulties involving transportation (p=0.04) and structural accessibility to dental services (p<0.01) among children and adolescents with severe CP. In addition, the more severe the CP, the greater the difficulty of accessibility (OR=4.09,) and the lower the income (OR=8.80), the greater the motor impairment. Conclusion: Despite the availability of access to dental services, low-income families have more severe CP patients, contributing to the daily difficulties already faced by them in oral health care.

A new insight into the definition of microcephaly in Zika congenital syndrome era.

This study aimed to compare the anthropometric measurements and body proportionalities of neonates born before the Zika virus epidemic with those born during this period. We compared 958 neonates born during the pre-Zika epidemic with 264 neonates born during the epidemic period. The newborns had their head circumference, weight, and length classified according to the Fenton & Kim growth chart. We considered disproportionate those individuals that presented microcephaly and adequate weight or length for sex and gestational age, and those whose head circumferences were lower than the ratio ((length / 2) + 9.5) - 2.5cm. We estimated the frequencies of Zika positivity and brain imaging findings among neonates with microcephaly born during the epidemic period, concerning the anthropometric and body proportionality parameters. Low weight and proportionate microcephaly were similar among newborns from both periods. However, the frequencies of newborns with microcephaly with a very low length and disproportionate microcephaly were higher among the neonates of the epidemic period with brain abnormalities and positive for Zika virus. We conclude that, at birth, the disproportion between head circumference and length can be an indicator of the severity of microcephaly caused by congenital Zika.

Excess weight among women in a low-income urban community: socioeconomic, demographic and reproductive factors. / Excesso de peso em mulheres de uma comunidade urbana de baixa renda: fatores socioeconômicos, demográficos e reprodutivos.

The aim of the present study was to investigate the prevalence of excess weight and associated factors in women of reproductive age living in a low-income community. A cross-sectional study was conducted with a sample of 663 women 15 to 49 years of age residing in the neighborhood of Coelhos in the city of Recife, Brazil. Body mass index (BMI)-for-age was used to classify the nutritional status of the adolescents (15 to 19 years of age), adopting Z-score of ≥+1 for the definition of overweight. For the adults, BMI≥25.0 kg/m² was considered indicative of overweight. Socioeconomic, demographic and reproductive variables were analyzed as possible factors associated with overweight. The prevalence of excess weight was found in two thirds of the sample. The results of the Poisson multiple regression analysis showed a significantly higher prevalence of excess weight with the advance in age, among those with a younger menarche age, those who had three or more pregnancies, those living with their partner and those self-declared black or white. Multiparity was the only factor associated with excess weight that could be modified, which underscores the importance of prenatal and family planning services to its prevention and control.

O objetivo do estudo foi avaliar a prevalência de excesso de peso e fatores associados nas mulheres em idade reprodutiva, residentes em uma comunidade de baixa renda. Estudo transversal cuja amostra consistiu em 663 mulheres, na faixa etária de 15 a 49 anos, domiciliadas na comunidade dos Coelhos, Recife-PE. O IMC para idade foi utilizado para classificar o estado nutricional de mulheres entre 15 e 19 anos, considerando ≥+1 escore Z para definir excesso de peso. Nas mulheres com idade superior a 19 anos, considerou-se o IMC≥25,0 kg/m². Variáveis socioeconômicas, demográficas e reprodutivas foram analisadas como possíveis fatores associados ao excesso de peso. A prevalência do excesso de peso foi observada em dois terços das mulheres estudadas. Os resultados da análise de regressão múltipla de Poisson mostraram uma prevalência significantemente maior do excesso de peso em mulheres com o avançar da idade cronológica, com menor idade da menarca, que tiveram três ou mais gestações, que coabitavam com o companheiro e se autodenominaram com cor preta ou cor branca. A multiparidade foi o único fator associado ao excesso de peso passível de modificação, o que reforça a necessidade de destacar a importância dos serviços de pré-natal e planejamento familiar na sua prevenção e controle.

BIRTH WEIGHT AND OVERWEIGHT IN ADOLESCENTS: THE ERICA PROJECT IN THE CITY OF RECIFE, PERNAMBUCO.

OBJECTIVE: To verify the association of anthropometric parameters at birth, socioeconomic and biological variables, physical activity, and parental nutritional status with overweight and abdominal obesity in adolescents. METHODS: A cross-sectional study was carried out on 39 public and private schools in Recife (state of Pernambuco, Brazil). The sample consisted of 1,081 teenagers aged from 12 to 17 years. Data were collected from the Study of Cardiovascular Risks in Adolescents (ERICA). Body mass index according to age (BMI-for-age), waist circumference (WC), and waist-to-height ratio (WtHR) were considered as outcome variables, whereas the explanatory variables were birth weight, Röhrer's Ponderal Index (RPI), biological and socioeconomic variables, physical activity, and parental nutritional status. The crude and adjusted prevalence ratios (PR) for the studied association were estimated by Poisson Regression. RESULTS: The multivariate Poisson regression showed that the variable that remained significantly associated with overweight in adolescence was maternal overweight, PR=1.86 (95% confidence interval [95%CI] 1.09-3.17). High birth weight also remained significantly associated with abdominal obesity assessed by WC, PR=3.25 (95%CI 1.0-9.74). CONCLUSIONS: High birth weight may be a marker for abdominal obesity in adolescence; and high maternal BMI, for overweight.

Effects of a teacher training intervention on teachers' and students' motivation to physical education class / Efeitos de uma intervenção de formação de professores na motivação de professores e alunos para a aula de educação física

ABSTRACT The present study evaluated the effects of a teacher training intervention, based on Self-Determination Theory, on teachers' and students' motivation in physical education class. This is a pre-post quasi-experimental study with 4 physical education teachers and 611 students from four public schools. A handbook was developed and teacher training sessions were conducted. Statistical analysis consisted of paired t-tests and general linear model repeated measures to assess teachers' self-determined motivation and linear mixed effect regression to evaluate students' motivation. A significant increase in teachers' and students' motivation score was observed after the intervention. Among teacher, we verified an increase in self-determined motivation. Among students there were significant interaction time by group in Extrinsic Motivation Identified Regulation (F=5.6), Extrinsic Motivation External Regulation (F=7.41), Amotivation (F=5.32) and Self-determined Motivation (F=4.87). Also, Intrinsic Motivation significantly declined with age for boys (β= -0.151) and girls (β= -0.121) as well as Extrinsic Motivation Introjected Regulation for girls β= (-0.141). Training sessions can support teachers in planning lessons resulting in increasing teacher and students' motivation in physical education classes. However, this strategy was not enough to improve intrinsic motivation during the investigated period.

RESUMO O presente estudo avaliou os efeitos de uma intervenção com professores, baseada na Teoria da Autodeterminação, sobre a motivação de professores e alunos para a aula de educação física (EF). É um estudo quase-experimental do tipo antes e depois com 4 professores de EF e 611 alunos. Foi elaborado um manual e realizadas sessões de formação de professores. Análise estatística incluiu testes t pareados e medidas repetidas através do modelo linear geral e da regressão linear de efeito misto. Um aumento significante no escore de motivação de professores e alunos foi observado após a intervenção. Entre os professores verificou-se um aumento na motivação auto-determinada. Entre os alunos houve interação significante entre tempo por grupo (Motivação Extrínseca Regulação Identificada (F=5,6), Motivação Extrínseca Regulação Externa (F=7,41), Amotivação (F=5,32) e Motivação Autodeterminada (F=4,87). Além disso, a Motivação Intrínseca diminuiu significantemente com a idade para rapazes (β= -0.151) e moças (β= -0.121), bem como a Motivação Externa Regulação Introjetada para moças (β= -0.141). Sessões de formação podem apoiar os professores no planejamento resultando no aumento da motivação dos professores e alunos nas aulas de EF. No entanto, esta estratégia não foi suficiente para melhorar a motivação intrínseca no período investigado.

Globalização e Processamento de Alimentos: Consumo Alimentar no Nordeste Brasileiro / Globalization and Food Processing: Food Consumption in Northeastern Brazil

Introdução: O atual modelo globalizado de produção de alimentos acarreta homogeneização na alimentação, com diminuição no consumo de alimentos in natura e grande participação de ultraprocessados. Objetivo: Investigar os fatores associados ao consumo alimentar de adultos, considerando os níveis de processamento de alimentos. Métodos: Estudo transversal com adultos no estado de Pernambuco que avaliou o consumo alimentar e variáveis socioeconômicas, demográficas, segurança alimentar e outras relacionadas ao modo e prática de aquisição de alimentos. Foi utilizado questionário de frequência alimentar para investigação do consumo, com divisão dos alimentos conforme o nível de processamento, com posterior análise através de escores. Avaliou-se a associação entre consumo alimentar e variáveis explicativas através dos testes "U" de Mann Whitney e Kruskal Wallis, com aplicação, neste último caso, do teste "U" de Mann Whitney a posteriori. Foram consideradas estatisticamente significantes associações com valor de p<0,05. Resultados: Foram entrevistados 1.066 adultos, cuja maioria possuía baixa escolaridade, baixa renda, com participação em programa de transferência de renda e em situação de insegurança alimentar. Essas variáveis mostraram associação com o consumo de determinados grupos alimentares. Também foram observadas diferenças no consumo conforme características como local de moradia, sexo, faixa etária, modo de aquisição de alimentos, local de compra e hábito de leitura do rótulo. Conclusões: Diante do contexto globalizado de estímulo aos industrializados, aspectos como gênero, condições econômicas, local de moradia, ambiente e práticas de compra de alimentos podem se mostrar como protetores para maior consumo de alimentos minimamente processados ou de risco para o consumo de ultraprocessados.

Introduction: The current globalized model of food production leads to the homogenization of diet, with a reduction in the consumption of unprocessed foods and the considerable participation of ultra-processed foods. Objective: Investigate factors associated with food consumption among adults considering the degree of food processing. Methods: A cross-sectional study was conducted with adults in the state of Pernambuco involving the assessment of food consumption. Data were also collected on sociodemographic characteristics, food insecurity and aspects related to food acquisition. A food frequency questionnaire was used to investigate food intake, with the categorization of foods according to the degree of processing and the subsequent analysis of consumption scores. Associations between food consumption and explanatory variables were evaluated using the Mann-Whitney U test and Kruskal- Wallis test, the latter of which was complemented with the post hoc Mann-Whitney U test. Associations with a p-value <0.05 were considered statistically significant. Results: One thousand sixty-six adults were interviewed. Most had a low level of schooling and low income, were beneficiaries of the income transfer program and were in a situation of food insecurity. These variables were associated with the consumption of particular food groups. Differences in consumption were found according to place of residence, sex, age group, mode of food acquisition, place of purchase and the habit of reading food labels. Conclusions: In the globalized context that stimulates the consumption of industrialized foods, aspects such as sex, economic status, place of residence and food purchasing environment and practices can serve as protective factors that ensure the greater consumption of minimally processed foods or risk factors for the consumption of ultra-processed foods products.

A new insight into the definition of microcephaly in Zika congenital syndrome era / Uma nova visão da definição de microcefalia na era da síndrome congênita do vírus Zika / Una nueva perspectiva en la definición de microcefalia durante la era del síndrome congénito Zika

Abstract: This study aimed to compare the anthropometric measurements and body proportionalities of neonates born before the Zika virus epidemic with those born during this period. We compared 958 neonates born during the pre-Zika epidemic with 264 neonates born during the epidemic period. The newborns had their head circumference, weight, and length classified according to the Fenton & Kim growth chart. We considered disproportionate those individuals that presented microcephaly and adequate weight or length for sex and gestational age, and those whose head circumferences were lower than the ratio ((length / 2) + 9.5) - 2.5cm. We estimated the frequencies of Zika positivity and brain imaging findings among neonates with microcephaly born during the epidemic period, concerning the anthropometric and body proportionality parameters. Low weight and proportionate microcephaly were similar among newborns from both periods. However, the frequencies of newborns with microcephaly with a very low length and disproportionate microcephaly were higher among the neonates of the epidemic period with brain abnormalities and positive for Zika virus. We conclude that, at birth, the disproportion between head circumference and length can be an indicator of the severity of microcephaly caused by congenital Zika.

Resumo: O estudo buscou comparar as medidas antropométricas e proporções corporais de recém-nascidos do período pré-Zika com os nascidos durante a epidemia de microcefalia congênita pelo vírus Zika. Comparamos 958 recém-nascidos do período pré-Zika com 264 nascidos durante o período epidêmico. Foram classificados o perímetro cefálico, peso e comprimento dos neonatos de acordo com a escala de crescimento de Fenton & Kim. Consideramos desproporcionais aqueles neonatos que apresentaram microcefalia e peso ou comprimento adequado para sexo e idade gestacional, além daqueles cujo perímetros cefálicos eram menores que a razão ((comprimento / 2) + 9,5) -2,5cm. Estimamos as frequências de positividade para Zika e resultados de imagens de cerebrais entre bebês com microcefalia nascidos no período epidêmico, em relação aos parâmetros antropométricos e de proporcionalidade corporal. Baixo peso e microcefalia proporcional foram semelhantes entre recém-nascidos de ambos os períodos. Entretanto, as frequências de neonatos com microcefalia e com comprimento muito curto e microcefalia desproporcional foram muito maiores entre os nascidos no período epidêmico com anomalias cerebrais e positivos para Zika. Concluímos que a desproporção entre perímetro cefálico e comprimento ao nascer pode ser um indicador da gravidade da microcefalia causada pela síndrome congênita do Zika vírus.

Resumen: El objetivo del estudio fue comparar las medidas antropométricas y de proporcionalidad corporal en neonatos nacidos durante un período pre-Zika, con quienes nacieron durante la epidemia de microcefalia por el síndrome congénito Zika. Comparamos a 958 neonatos nacidos durante la epidemia pre-Zika, con 264 neonatos nacidos durante el período epidémico. A los recién nacidos se les clasificó su circunferencia de la cabeza, peso y longitud según la tabla de crecimiento Fenton & Kim. Consideramos desproporcionados a quienes presentaron microcefalia y peso o longitud adecuada para sexo y edad gestacional, y quienes tenían unas circunferencias de cabeza cuyo ratio era menor que ((longitud / 2) + 9.5) - 2.5cm. Estimamos las frecuencias de positividad para Zika, así como los resultados de imágenes cerebrales entre neonatos nacidos con microcefalia durante el período epidémico, en relación con parámetros antropométricos y de proporcionalidad corporal. Bajo peso y microcefalia proporcional fueron similares entre los recién nacidos de ambos períodos. No obstante, las frecuencias de recién nacidos con microcefalia con una longitud muy baja y microcefalia desproporcionada fueron mayores entre los neonatos del período epidémico, con anormalidades cerebrales y positivos para Zika. Concluimos que la desproporción entre la circunferencia de cabeza y longitud al nacer puede ser un indicador de la gravedad de la microcefalia, causada por el Zika congénito.

Birth weight and overweight in adolescents: the erica project in the city of recife, pernambuco / Peso ao nascer e excesso de peso em adolescentes: projeto erica na cidade do recife, pernambuco

ABSTRACT Objective: To verify the association of anthropometric parameters at birth, socioeconomic and biological variables, physical activity, and parental nutritional status with overweight and abdominal obesity in adolescents. Methods: A cross-sectional study was carried out on 39 public and private schools in Recife (state of Pernambuco, Brazil). The sample consisted of 1,081 teenagers aged from 12 to 17 years. Data were collected from the Study of Cardiovascular Risks in Adolescents (ERICA). Body mass index according to age (BMI-for-age), waist circumference (WC), and waist-to-height ratio (WtHR) were considered as outcome variables, whereas the explanatory variables were birth weight, Röhrer's Ponderal Index (RPI), biological and socioeconomic variables, physical activity, and parental nutritional status. The crude and adjusted prevalence ratios (PR) for the studied association were estimated by Poisson Regression. Results: The multivariate Poisson regression showed that the variable that remained significantly associated with overweight in adolescence was maternal overweight, PR=1.86 (95% confidence interval [95%CI] 1.09-3.17). High birth weight also remained significantly associated with abdominal obesity assessed by WC, PR=3.25 (95%CI 1.0-9.74). Conclusions: High birth weight may be a marker for abdominal obesity in adolescence; and high maternal BMI, for overweight.

RESUMO Objetivo: Verificar a associação de parâmetros antropométricos ao nascer, variáveis socioeconômicas e biológicas, atividade física e estado nutricional parental com excesso de peso e obesidade abdominal de adolescentes. Métodos: Este estudo transversal foi realizado em 39 escolas públicas e privadas de Recife (PE). A amostra consistiu em 1.081 adolescentes entre 12 e 17 anos de idade, provenientes do Estudo de Riscos Cardiovasculares em Adolescentes (ERICA). Estabeleceram-se como variáveis de desfecho o índice de massa corpórea para a idade (IMC/I), a circunferência da cintura (CC) e a relação cintura/estatura (RCEst), enquanto as explanatórias foram o peso ao nascer, o índice ponderal de Röhrer (IPR), as variáveis biológicas e socioeconômicas, a atividade física e o estado nutricional dos pais. Estimaram-se as razões de prevalência (RP) brutas e ajustadas para as associações estudadas pela regressão de Poisson. Resultados: A regressão multivariada de Poisson mostrou que a variável mantida como significantemente associada ao excesso de peso na adolescência foi o excesso de peso materno, RP=1,86 (intervalo de confiança de 95% [IC95%] 1,09-3,17). O peso elevado ao nascer também permaneceu bastante associado à obesidade abdominal avaliada pela CC, RP=3,25 (IC95% 1,08-9,74). Conclusões: O peso elevado ao nascer constituiu marcador para a obesidade abdominal na adolescência; e o IMC materno elevado, para o excesso de peso.

Cuidados em saúde bucal a crianças e adolescentes com paralisia cerebral: percepção de pais e cuidadores / Oral health care for children and adolescents with cerebral palsy: perceptions of parents and caregivers

Resumo Objetivou-se avaliar os cuidados em saúde bucal de crianças/adolescentes com Paralisia Cerebral (PC) segundo a gravidade, através da percepção dos pais/cuidadores. Estudo série de casos realizado em serviços de saúde de Pernambuco com 94 mães/cuidadores de sujeitos com PC entre 5 e 18 anos. Avaliaram-se fatores socioeconômicos, demográficos, cuidados em saúde bucal e uso de serviços odontológicos (SO). O Sistema de Classificação da Função Motora Grossa mostrou 67% com comprometimento motor grave. Indivíduos com PC grave tiveram frequência significantemente maior de pertencerem a famílias com renda mais baixa (89%, p < 0,001), residirem no interior (44%, p < 0,005), terem dificuldades de transporte (60%, p = 0,04) e acessibilidade aos SO (88%, p = 0,009) e maior necessidade de higiene bucal (67%, p = 0,008) realizada pelas mães (94%, p < 0,001). Apesar das barreiras de acesso aos SO, o mesmo foi facilitado para aqueles com PC grave, com uso precoce dos SO, mas com baixa oferta de dentistas e de humanização. Esses resultados informam problemas relacionados aos cuidados diários em saúde bucal, contexto de vida das famílias, de apoio institucional e de qualidade dos SO a serem enfrentados com políticas públicas socioeconômicas e de saúde integrais inclusivas e equânimes.

Abstract The aim was to evaluate the oral health care of children/adolescents with Cerebral Palsy (CP) according to severity through the perceptions of parents/caregivers. A case series study was conducted at health services in the state of Pernambuco, Brazil with 94 mothers/caregivers of subjects with CP from 5 and 18 years old. Sociodemographic factors, oral health care and use of dental services (DS) were evaluated. The Gross Motor Function Classification System showed 67% with severe motor impairment. Subjects with severe CP had significantly higher frequencies of belonging to families with lower income (89%, p < 0.001), living in the interior (44%, p < 0.005), having transportation difficulties (60%, p = 0.04), difficulty regarding access to DS (88%, p = 0.009) and a greater need for oral hygiene (67%, p = 0.008), which was performed exclusively by the caregiver (94%, p < 0.001). Despite identified access barriers, dental care was facilitated for those with severe CP, early DS use, but low availability of dentists and low degree of humanization were cited as major problems. These results reveal problems related to daily oral health care, family living context, institutional support and quality of DS that should be addressed in comprehensive, inclusive, equitable social and economic public policies.

Oral health care for children and adolescents with cerebral palsy: perceptions of parents and caregivers. / Cuidados em saúde bucal a crianças e adolescentes com paralisia cerebral: percepção de pais e cuidadores.

The aim was to evaluate the oral health care of children/adolescents with Cerebral Palsy (CP) according to severity through the perceptions of parents/caregivers. A case series study was conducted at health services in the state of Pernambuco, Brazil with 94 mothers/caregivers of subjects with CP from 5 and 18 years old. Sociodemographic factors, oral health care and use of dental services (DS) were evaluated. The Gross Motor Function Classification System showed 67% with severe motor impairment. Subjects with severe CP had significantly higher frequencies of belonging to families with lower income (89%, p < 0.001), living in the interior (44%, p < 0.005), having transportation difficulties (60%, p = 0.04), difficulty regarding access to DS (88%, p = 0.009) and a greater need for oral hygiene (67%, p = 0.008), which was performed exclusively by the caregiver (94%, p < 0.001). Despite identified access barriers, dental care was facilitated for those with severe CP, early DS use, but low availability of dentists and low degree of humanization were cited as major problems. These results reveal problems related to daily oral health care, family living context, institutional support and quality of DS that should be addressed in comprehensive, inclusive, equitable social and economic public policies.

Objetivou-se avaliar os cuidados em saúde bucal de crianças/adolescentes com Paralisia Cerebral (PC) segundo a gravidade, através da percepção dos pais/cuidadores. Estudo série de casos realizado em serviços de saúde de Pernambuco com 94 mães/cuidadores de sujeitos com PC entre 5 e 18 anos. Avaliaram-se fatores socioeconômicos, demográficos, cuidados em saúde bucal e uso de serviços odontológicos (SO). O Sistema de Classificação da Função Motora Grossa mostrou 67% com comprometimento motor grave. Indivíduos com PC grave tiveram frequência significantemente maior de pertencerem a famílias com renda mais baixa (89%, p < 0,001), residirem no interior (44%, p < 0,005), terem dificuldades de transporte (60%, p = 0,04) e acessibilidade aos SO (88%, p = 0,009) e maior necessidade de higiene bucal (67%, p = 0,008) realizada pelas mães (94%, p < 0,001). Apesar das barreiras de acesso aos SO, o mesmo foi facilitado para aqueles com PC grave, com uso precoce dos SO, mas com baixa oferta de dentistas e de humanização. Esses resultados informam problemas relacionados aos cuidados diários em saúde bucal, contexto de vida das famílias, de apoio institucional e de qualidade dos SO a serem enfrentados com políticas públicas socioeconômicas e de saúde integrais inclusivas e equânimes.

Influence of MBL2 and NOS3 polymorphisms on spontaneous preterm birth in North East Brazil: genetics and preterm birth.

Background: The mannose-binding lectin (MBL2) and nitric oxide synthase 3 (NOS3) genes are associated with the immune response against inflammatory processes, have been reported as possibly related with premature birth. Until now, most of the researches regarding the genetic influence of prematurity have revealed limited results because only investigating the child or the mothers' genotypes, thus not exploring the possible effects of interactions between these genotypes or the interactions with environmental factors related to the duration of pregnancy.Objective: We performed a replica study investigating the influence of single nucleotide polymorphisms (SNPs) in MBL2 and NOS3 genes on premature birth, also considering socioeconomic, demographic, and gestational factors.Materials and methods: We conducted a case-control study with 189 mother-infant dyads, with 104 spontaneous preterm births and 85 term births from Recife, Brazil. We used peripheral blood samples and umbilical cord samples to extract DNA. Functional SNPs at exon 1 and promoter region of MBL2 and NOS3 RS1799983 SNP were genotyped using direct sequencing and fluorescent allelic specific TaqMan® assays respectively. Data were analyzed using the Statistical Package for the Social Sciences (SPSS®) program with bivariate association and logistic multivariate regression tests.Results: We observed a prevalence of MBL2 wild-type genotype in the mother-infant dyad of the preterm group and polymorphic genotype in the mother-infant dyad of term birth. The haplotype LYA predominated in our sample, being more frequent in the preterm group, while the haplotype LYB, correlated with lower levels of MBL protein, was more frequent in the term birth group. About NOS3 RS1799983 SNP, the G/G genotype was more frequent throughout the sample. The heterozygous genotype predominated among women from the preterm group, showed a borderline difference between the groups. When MBL2 genotypes of the mother and son were analyzed together, codon 54 of MBL2 remained associated with prematurity. When the variables with p value lower than .20 in the bivariate analysis were analyzed by logistic regression, the low weight of the pregnant woman in relation to the gestational age, the occurrence of preterm premature rupture of membranes, urinary tract infection during birth and maternal history of other premature births were risk factors to prematurity. On the other hand, the presence of B allele at codon 54 of maternal MBL2 was a protective factor for the occurrence of spontaneous premature birth. In contrast, a borderline association was established between the maternal genetic variation within NOS3 gene and the outcome studied.Conclusions: Our study, limited by the small number of patients enrolled, indicates that MBL2 and NOS3 functional SNPs are associated with the occurrence of spontaneous prematurity and the regulation of the maternal inflammatory response. Despite these results are in agreement with previously reports, our findings do not replicate the ones reported in a large genome-wide association study performed on quite high number of subjects. Thus, we can conclude that MBL2 and NOS3 functional SNPs are plausible candidate risk factors just in few preterm birth cases, and consequently they cannot be included in the general diagnostic practice.

Validação do Perceived Locus Of Causality Questionnaire para avaliação da motivação nas aulas de Educação Física / Validation of Perceived Locus Of Causality Questionnaire for motivation assessment on Physical Education classes

A Educação Física possui um papel central durante os anos escolares, pois a participação de forma regular pode proporcionar, dentre outros, benefícios biológicos, psicológicos e acadêmicos. Conhecer a motivação dos estudantes pode contribuir no planejamento de estratégias para melhorar a participação nas aulas. Para o conhecimento da motivação faz-se necessário à utilização de instrumentos, que muitas vezes não são validados para a população a qual se quer investigar, dificultando assim a comparação dos resultados obtidos. O presente estudo teve como objetivo realizar a adaptação transcultural e avaliar as propriedades psicométricas do Perceived Locus of Causality Questionnaire (PLOCQ) que visa medir as dimensões motivacionais definidas em um continuum da Teoria da Autodeterminação para articipação nas aulas de Educação Física Escolar. As etapas de validação foram: tradução do instrumento, retro-tradução, revisão técnica e avaliação da equivalência semântica, validação do conteúdo, avaliação do instrumento pelos especialistas e população-alvo e avaliação das propriedades psicométricas. O instrumento foi aplicado a 464 estudantes (58,4% de moças) do ensino médio com idade entre 13 e 17 anos. Foram realizadas a adaptação transcultural e avaliação das propriedades psicométricas por meio da reprodutibilidade, análise de consistência interna, análise fatorial exploratória (AFE) e confirmatória (AFC). Os itens da escala apresentaram boa consistência interna com variação do coeficiente α de Cronbach de 0,71 a 0,79 e boa reprodutibilidade teste-reteste (Kappa entre 0,61 a 0,88). A análise fatorial exploratória identificou cinco componentes e vinte itens que explicaram 57,9% da variância do questionário. O modelo final da análise fatorial confirmatória foi significativo (RMSEA de 0,071; GFI de 0,91, RMSR de 0,04 e CFI de 0,95). O instrumento poderá ser utilizado, com um elevado grau de confiança, em futuras investigações que pretendam avaliar a motivação dos estudantes no contexto das aulas de Educação Física no Brasil...(AU)

The physical education class has a central role during scholar years because a regular participation could provide among others biological, psychological and academic benefits. Knowing student motivation can contribute to planning strategies to improve participation in class. To know the motivation, it is necessary to use instruments, which are often not validated for the target population, making it difficult to compare the results obtained. The objective of this study was to translate and perform a cross-cultural adaptation and analyze psychometric properties of the Perceived Locus of Causality Questionnaire (PLOCQ) that aims to measure the motivational dimensions forms defined on a continuum of Self-determination Theory for participation in physical education classes. The validation stages were translation of the instrument, back translation, technical review and evaluation of semantic equivalence, validation of content, evaluation of the instrument by specialists and target population and evaluation of psychometric properties. This instrument was administered to 464 high school students (58.4% female) aged 13 to 17 years. The stages of cultural adaptation were conducted as well as evaluation of the psychometric properties through reproducibility, internal consistency and exploratory factor analysis. The items of the scale showed good internal consistency with coefficient α Cronbach ranging from 0.71 to 0.79 and good test-retest reproducibility (Kappa coefficient ranged from 0.61 to 0.88). Exploratory factor analysis identified five components that explained 57.9% of the variance of the questionnaire items. The final model of confirmatory factor analysis was significant (RMSEA of 0.071, GFI of 0.91, RMSR of 0.04 and IFC of 0.95). We conclude that this tool can be used with a high degree of confidence in future investigations aiming to assess the student motivation in the context of physical education classes in Brazil...(AU)

Mental health of children exposed to intimate partner violence against their mother: A longitudinal study from Brazil.

BACKGROUND: Exposure to intimate partner violence (IPV) is an important adverse childhood experience, but there are few longitudinal studies in low and middle-income countries. OBJECTIVE: To investigate the consequences of exposure to IPV for a child's mental health. PARTICIPANTS AND SETTING: 614 mother-child pairs were evaluated in a poor urban district in Recife, northeastern Brazil. METHODS: Women were interviewed in pregnancy, postpartum and six to nine years after delivery, and asked about their experience of IPV, and the exposure of their child to violence. The Strengths and Difficulties Questionnaire (SDQ) was completed by child's mother and teacher. Ten types of child experience of IPV and the age of onset of exposure were compared with the child's behavioral profile at school age. RESULTS: The mothers reported that 372/614 (60.6%) children had been exposed to IPV. The commonest types of child exposure to IPV were "prenatally", "overheard", "eyewitnessed", and 10.0% of children were physically or verbally involved in the IPV. Mothers reported high SDQ Total Difficulties scores in 71.7% of all children exposed to IPV and teachers in 59.8%. Multivariate logistic regression analysis demonstrated the strongest association with behavioral difficulties was with exposure to IPV in the age group 1-2 years (OR 2.5 [95% CI: 1.3-4.8]). CONCLUSION: Young children are sensitive to the age of first exposure to IPV and to the type of IPV. Interventions to reduce IPV should be targeted on vulnerable women from poor urban communities during their pregnancies and in the first two years of their child's life.